The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2014
Filed:
Sep. 28, 2012
Applicant:
Nerviano Medical Sciences S.r.l., Nerviano, IT;
Inventors:
Maurizio Pulici, Caponago, IT;
Paolo Polucci, Cassina Rizzardi, IT;
Assignee:
Nerviano Medical Sciences S.R.L., Nerviano (MI), IT;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 31/4162 (2006.01); A61K 31/454 (2006.01); C07D 401/14 (2006.01); C07D 401/12 (2006.01); C07D 495/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
There are provided bicyclic carbonylamino-pyrazoles of formula (I), wherein the variables are as specified in the claims, for use as medicament, in particular for the treatment of diseases due to the malfunctioning of protein kinases (PKs), such as cancer, pharmaceutical compositions comprising such carbamoyl derivatives, and their use as prodrugs of therapeutically active agents. Method of treatment and some new bicyclic carbonylamino-pyrazoles are also object of the present invention.