The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2014
Filed:
Nov. 11, 2009
Zhaoning Zhu, Plainsboro, NJ (US);
William J. Greenlee, Teaneck, NJ (US);
Hongmei LI, Warren, NJ (US);
Monica L. Vicarel, North Brunswick, NJ (US);
Jun Qin, Edison, NJ (US);
Pawan Kumar Dhondi, Elizabeth, NJ (US);
Xianhai Huang, Warren, NJ (US);
Anandan Palani, Bridgewater, NJ (US);
Xiaoxiang Liu, River Vale, NJ (US);
Zhong-yue Sun, Parlin, NJ (US);
Hubert B. Josien, Jersey City, NJ (US);
Ruo Xu, Watchung, NJ (US);
David James Cole, Springfield, NJ (US);
Duane A. Burnett, Bernardsville, NJ (US);
Chad E. Bennett, Metuchen, NJ (US);
Troy Mccracken, Garwood, NJ (US);
Malcolm Maccoss, Seabrook Island, SC (US);
Zhaoning Zhu, Plainsboro, NJ (US);
William J. Greenlee, Teaneck, NJ (US);
Hongmei Li, Warren, NJ (US);
Monica L. Vicarel, North Brunswick, NJ (US);
Jun Qin, Edison, NJ (US);
Pawan Kumar Dhondi, Elizabeth, NJ (US);
Xianhai Huang, Warren, NJ (US);
Anandan Palani, Bridgewater, NJ (US);
Xiaoxiang Liu, River Vale, NJ (US);
Zhong-Yue Sun, Parlin, NJ (US);
Hubert B. Josien, Jersey City, NJ (US);
Ruo Xu, Watchung, NJ (US);
David James Cole, Springfield, NJ (US);
Duane A. Burnett, Bernardsville, NJ (US);
Chad E. Bennett, Metuchen, NJ (US);
Troy McCracken, Garwood, NJ (US);
Malcolm MacCoss, Seabrook Island, SC (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
In its many embodiments, the present invention provides a novel class of heterocyclic compounds of the formula: as modulators of gamma secretase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more disease associated with the central nervous system using such compounds or pharmaceutical compostions.