The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2014
Filed:
Dec. 15, 2006
Masatoshi Kiuchi, Osaka, JP;
Kaoru Marukawa, Osaka, JP;
Nobutaka Kobayashi, Osaka, JP;
Kunio Sugahara, Osaka, JP;
Masatoshi Kiuchi, Osaka, JP;
Kaoru Marukawa, Osaka, JP;
Nobutaka Kobayashi, Osaka, JP;
Kunio Sugahara, Osaka, JP;
Mitsubishi Tanabe Pharma Corporation, Osaka-shi, JP;
Abstract
A novel amine compound represented by the following formula (I), which is superior in immunosuppressive action, rejection suppressive action and the like, and shows reduced side effects such as bradycardia and the like, or a pharmaceutically acceptable acid addition salt thereof, or hydrates thereof, or solvate, as well as a pharmaceutical composition containing this compound and a pharmaceutically acceptable carrier. wherein R is a hydrogen atom or P(═O)(OH), X is an oxygen atom or a sulfur atom, Y is CHCHor CH═CH, Ris cyano or alkyl having a carbon number of 1 to 4 and substituted by a halogen atom(s), Ris alkyl having a carbon number of 1 to 4 and optionally substituted by a hydroxyl group(s) or a halogen atom(s), Rand Rmay be the same or different and each is a hydrogen atom or alkyl having a carbon number of 1 to 4, and n is 5-8.