The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 19, 2014

Filed:

Aug. 30, 2007
Applicants:

Joerg Werner Baier, Verona, WI (US);

Robert Charles Mierendorf, Verona, WI (US);

Anthony Charles Grabski, Blue Mounds, WI (US);

Andrew Paul Wilke, Madison, WI (US);

Anil Rajaram Oroskar, Oak Brook, IL (US);

Inventors:

Joerg Werner Baier, Verona, WI (US);

Robert Charles Mierendorf, Verona, WI (US);

Anthony Charles Grabski, Blue Mounds, WI (US);

Andrew Paul Wilke, Madison, WI (US);

Anil Rajaram Oroskar, Oak Brook, IL (US);

Assignee:

Semba Biosciences, Inc., Madison, WI (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
F16K 11/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides devices and methods for micro-scale simulated moving bed chromatography (SMB) for continuous preparation of analytic quantities of highly pure fractions of target molecules. The present apparatus and method of the invention is adapted in a preferred embodiment to separations by affinity chromatography involving three discontinuous liquid flow loops. An alternative embodiment of affinity chromatography utilizes standard SMB operating under isocratic conditions.


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