The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 2014
Filed:
Feb. 27, 2012
Applicant:
Rashida A. Karmali, Brooklyn, NY (US);
Inventor:
Rashida A. Karmali, Brooklyn, NY (US);
Assignee:
Savvipharm Inc, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 15/252 (2006.01); C07D 239/557 (2006.01); A61K 38/12 (2006.01); A61K 38/20 (2006.01); A61K 31/704 (2006.01); A61K 31/513 (2006.01);
U.S. Cl.
CPC ...
C07H 15/252 (2013.01); A61K 38/12 (2013.01); A61K 38/2013 (2013.01); A61K 31/704 (2013.01); A61K 31/513 (2013.01);
Abstract
This invention is in the field of anthracycline family of drugs. More particularly, it concerns converting daunorubicin hydrochloride to an orotate salt and providing methods of improving the tolerability of daunorubicin in animals by reducing the adverse effects and toxicity in noncancerous tissues. Daunorubicin orotate provides a safer treatment for specific types of leukemias and neuroblastomas in adults and in pediatric patients.