The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 12, 2014

Filed:

Dec. 27, 2013
Applicant:

Astrazeneca Ab, Sodertalje, SE;

Inventors:

Jack Z. Gougoutas, Princeton, NJ (US);

Mary F. Malley, Princeton, NJ (US);

John D. DiMarco, Princeton, NJ (US);

Xiaotian S. Yin, Princeton, NJ (US);

Chenkou Wei, Princeton, NJ (US);

Jurong Yu, Princeton, NJ (US);

Truc Chi Vu, Princeton, NJ (US);

Gregory Scott Jones, Princeton, NJ (US);

Scott A. Savage, Princeton, NJ (US);

Assignee:

AstraZeneca AB, Sodertalje, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/403 (2006.01); C07D 209/02 (2006.01); C07D 209/52 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 209/52 (2013.01); A61K 45/06 (2013.01); A61K 31/403 (2013.01);
Abstract

Physical crystal structures of a compound of the formula I: are provided including the free base monohydrate thereof (form H-1) and the hydrochloric acid salt thereof, including hydrochloric acid salt containing 0.75 equivalent of HO (form H0.75-3) and hydrochloric acid salt containing 2 equivalents of HO (form H2-1), and hydrochloric acid salt Pattern P-5, preferably in substantially pure form, and other forms as described herein, pharmaceutical compositions containing structures of compound I or IA, processes for preparing same, intermediates used in preparing same, and methods of treating diseases such as diabetes using such structures.


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