The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 2014
Filed:
Nov. 27, 2012
Fundação Oswaldo Cruz, Rio de Janeiro, BR;
Nubia Boechat, Niterói, BR;
Marcus Vinicius Nora de Souza, Juiz de Fora, BR;
Alessandra Leda Valverde, Rio de Janeiro, BR;
Antoniana Ursine Krettli, Belo Horizonte, BR;
Fundação Oswaldo Cruz, Rio de Janeiro, BR;
Abstract
The present invention refers to new compounds represented by the general formula (I) where X is represented by the general formula (II) and Y is represented by the general formula (III). The relation X to Y may vary from 1:1 to 1:7. The radicals R, R, R, R, R, and Rin formula (II) are represented by: R=H, CF, CH, OCH, NH, halogen; R=H, CH, NH, halogen, NH—CHCH(CH)N(CH)(CHCHOH), CH(OH)-2(CHN), NH—R—N—(CH); R=H, m-OCHCF, NH; R=H, CH, OCH, NH, halogen; R=H, CH, CF, NH, halogen; R=H, CF, CH, NH, halogen, NH—R—N—(CH), NHCH(CH)(CH)NH; R=(CH), (CH), CHCHCH, (CH), (CH), CHCH(CH), (CH), (CH), (CH), (CH); R=CHCH(CH), CHCH(CH)CHCH, (CH), (CH), (CH), (CH)O(CH). This invention also refers to a process of preparation of these compounds (formula I), and antiparasitic pharmaceutical compositions thereof.