The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 2014
Filed:
Apr. 24, 2007
Adrian Folkes, Slough, GB;
Stephen Shuttleworth, Slough, GB;
Irina Chuckowree, Slough, GB;
Sally Oxenford, Slough, GB;
Nan Chi Wan, Slough, GB;
Georgette Castanedo, Redwood City, CA (US);
Richard Goldsmith, Belmont, CA (US);
Janet Gunzner, Berkeley, CA (US);
Tim Heffron, San Francisco, CA (US);
Simon Mathieu, Burlingame, CA (US);
Alan Olivero, Half Moon Bay, CA (US);
Daniel P. Sutherlin, South San Francisco, CA (US);
Bing-yan Zhu, Palo Alto, CA (US);
Adrian Folkes, Slough, GB;
Stephen Shuttleworth, Slough, GB;
Irina Chuckowree, Slough, GB;
Sally Oxenford, Slough, GB;
Nan Chi Wan, Slough, GB;
Georgette Castanedo, Redwood City, CA (US);
Richard Goldsmith, Belmont, CA (US);
Janet Gunzner, Berkeley, CA (US);
Tim Heffron, San Francisco, CA (US);
Simon Mathieu, Burlingame, CA (US);
Alan Olivero, Half Moon Bay, CA (US);
Daniel P. Sutherlin, South San Francisco, CA (US);
Bing-Yan Zhu, Palo Alto, CA (US);
F. Hoffmann-La Roche AG, Basel, CH;
Genentech, Inc., South San Francisco, CA (US);
Abstract
Compounds of Formulae Ia and Ib, and stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formula Ia and Ib for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.