The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 12, 2014

Filed:

Jun. 02, 2011
Applicants:

Alicia Regueiro-ren, Middletown, CT (US);

Zheng Liu, Beacon Falls, CT (US);

Jacob Swidorski, Southington, CT (US);

Nicholas A. Meanwell, East Hampton, CT (US);

Sing-yuen Sit, Meriden, CT (US);

Jie Chen, Madison, CT (US);

Yan Chen, Guilford, CT (US);

NY Sin, East Hampton, CT (US);

Inventors:

Alicia Regueiro-Ren, Middletown, CT (US);

Zheng Liu, Beacon Falls, CT (US);

Jacob Swidorski, Southington, CT (US);

Nicholas A. Meanwell, East Hampton, CT (US);

Sing-Yuen Sit, Meriden, CT (US);

Jie Chen, Madison, CT (US);

Yan Chen, Guilford, CT (US);

Ny Sin, East Hampton, CT (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/56 (2006.01); A61K 31/58 (2006.01); C07J 53/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, modified C-3 and C-28 betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors. These compounds are useful for the treatment of HIV and AIDS.


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