The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 2014
Filed:
Sep. 06, 2012
Ta-yuan Chang, Etna, NH (US);
Catherine C. Y. Chang, Etna, NH (US);
Elena Bryleva, Lebanon, NH (US);
Stephanie Murphy, West Lebanon, NH (US);
Maximillian A. Rogers, White River Junction, VT (US);
Ta-Yuan Chang, Etna, NH (US);
Catherine C. Y. Chang, Etna, NH (US);
Elena Bryleva, Lebanon, NH (US);
Stephanie Murphy, West Lebanon, NH (US);
Maximillian A. Rogers, White River Junction, VT (US);
Trustees of Dartmouth College, Hanover, NH (US);
Abstract
The present invention features methods for decreasing the size and density of amyloid plaques, decreasing cognitive decline associated with amyloid pathology, and treating Alzheimer's disease by selectively inhibiting the activity of Acyl-CoA:Cholesterol Acyltransferase 1, but not Acyl-CoA:Cholesterol Acyltransferase 2.