logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8802620 B1

PDFFull Text
Expired
Date of Patent:
Aug. 12, 2014

Filed:

Apr. 21, 2008

Demannosylated recombinant factor viii for the treatment of patients with haemophilia a

Applicants:

Abdessatar Sami Chtourou, Elancourt, FR;

Sébastien Lacroix-desmazes, Issy-les-Moulineaux, FR;

Srinivas Kaveri, Malakoff, FR;

Suryasarathi Dasgupta, Boston, MA (US);

Jagaadeesh Bayry, Issy-les-Moulineaux, FR;

Inventors:

Abdessatar Sami Chtourou, Elancourt, FR;

Sébastien Lacroix-Desmazes, Issy-les-Moulineaux, FR;

Srinivas Kaveri, Malakoff, FR;

Suryasarathi Dasgupta, Boston, MA (US);

Jagaadeesh Bayry, Issy-les-Moulineaux, FR;

Assignees:

Institut National de la Sante et de la Recherche Medicale (INSERM), Paris, FR;

LFB Biotechnologies, Les Ulis, FR;

Attorney:

Whitham Curtis Christofferson & Cook, PC

Primary Examiner:

Marcela M Cordero Garcia

Assistant Examiner:

Sergio Coffa

Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61P 7/00 (2006.01); A61K 38/36 (2006.01); A61P 7/02 (2006.01); C07K 14/745 (2006.01); A61K 38/37 (2006.01);
U.S. Cl.
CPC ...
Abstract

There is provided in accordance with the practice of this invention a demannosylated Factor VIII, the immunogenicity of which is substantially decreased or abolished in Human. The modified factor VIII is disclosed together with the modified amino acid sequence, changed by at least one substitution. The modified factor VIII is useful for hemophiliacs, either to avoid or prevent the action of inhibitory anti-FVIII antibodies.

Find Patent Forward Citations

Quick Actions:

Chtourou, Abdessatar. (2014). Demannosylated recombinant factor viii for the treatment of patients with haemophilia a (U.S. Patent No. 8802620). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8802620

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…