The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 12, 2014

Filed:

Oct. 17, 2011
Applicants:

Michael J. Adang, Athens, GA (US);

Rebecca Mcnall, Athens, GA (US);

Juan Luis Jurat Fuentes, Athens, GA (US);

Inventors:

Michael J. Adang, Athens, GA (US);

Rebecca McNall, Athens, GA (US);

Juan Luis Jurat Fuentes, Athens, GA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 25/00 (2006.01); C12N 1/20 (2006.01); C12Q 1/00 (2006.01); C12Q 1/02 (2006.01); C12Q 1/42 (2006.01); G01N 33/53 (2006.01); G01N 33/554 (2006.01); G01N 33/567 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
Abstract

The subject invention relates in part to the surprising and unexpected discovery that insects that are resistant toCry toxins have measurably altered alkaline phosphatase (ALP) activity as compared to insects that are susceptible to Cry toxins. This and other surprising discoveries reported herein have broad implications in areas such as managing and monitoring the development of insect resistance to B.t. toxins. For example, the subject invention provides a simple and fast assay (enzymatic or otherwise) for detecting ALP activity levels and thereby monitoring the development of resistance by insects to crystal protein insect toxins. There was no prior motivation or suggestion to go about resistance monitoring using this simple and easy approach.


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