The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 2014
Filed:
Mar. 09, 2010
Tokuzo Arao, Osaka, JP;
Kanae Kudo, Osaka, JP;
Kazuhiko Nakagawa, Osaka-Sayama, JP;
Kazuto Nishio, Osaka, JP;
Tokuzo Arao, Osaka, JP;
Kanae Kudo, Osaka, JP;
Kazuhiko Nakagawa, Osaka-Sayama, JP;
Kazuto Nishio, Osaka, JP;
Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;
Abstract
The present invention relates to biomarkers to monitor the activity of the compound 3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone or a pharmaceutically acceptable salt thereof, and especially its monoethanesulphonate salt form, when used alone or optionally in combination with further pharmaceutically active ingredients and/or further treatments, such as for example radiotherapy.