The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 2014
Filed:
Jul. 13, 2012
Austin L. Gurney, San Francisco, CA (US);
Fumiko Takada Axelrod, Palo Alto, CA (US);
Timothy Charles Hoey, Hillsborough, CA (US);
Cecile Chartier-courtaud, Palo Alto, CA (US);
Austin L. Gurney, San Francisco, CA (US);
Fumiko Takada Axelrod, Palo Alto, CA (US);
Timothy Charles Hoey, Hillsborough, CA (US);
Cecile Chartier-Courtaud, Palo Alto, CA (US);
OncoMed Pharmaceuticals, Inc., Redwood City, CA (US);
Abstract
The present invention relates to RSPO-binding agents and methods of using the agents for treating diseases such as cancer. The present invention provides antibodies that specifically bind human RSPO proteins and modulate β-catenin activity. The present invention further provides methods of using agents that modulate the activity of RSPO proteins, such as antibodies that specifically bind RSPO1, RSPO2, and/or RSPO3 and inhibit tumor growth. Also described are methods of treating cancer comprising administering a therapeutically effect amount of an agent or antibody of the present invention to a patient having a tumor or cancer.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile