The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2014

Filed:

Sep. 30, 2009
Applicants:

Kurtulus Izzetoglu, Drexel Hill, PA (US);

Kambiz Pourrezaei, Gladwynne, PA (US);

Banu Onaral, Philadelphia, PA (US);

Jay Charles Horrow, Wynnewood, PA (US);

Meltem Alkan Izzetoglu, Drexel Hill, PA (US);

Scott C. Bunce, Hummelstown, PA (US);

Inventors:

Kurtulus Izzetoglu, Drexel Hill, PA (US);

Kambiz Pourrezaei, Gladwynne, PA (US);

Banu Onaral, Philadelphia, PA (US);

Jay Charles Horrow, Wynnewood, PA (US);

Meltem Alkan Izzetoglu, Drexel Hill, PA (US);

Scott C. Bunce, Hummelstown, PA (US);

Assignees:

Drexel University, Philadelphia, PA (US);

Philadelphia Health & Education Corporation, Philadelphia, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 5/1455 (2006.01); A61M 16/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are methods and devices for measuring a state of anesthesia in a noninvasive manner. Optical techniques may be used to measure changes in a functional near-infrared (fNIR) signal, where the fNIR signal is received in response to directing wavelengths of light in a near-infrared range on a patient. The optical density change may be used to obtain a change in deoxyhemoglobin (deoxy-Hb) concentration and/or a change in an oxyhemoglobin concentration (oxy-Hb). The changes in the deoxy-Hb and/or the oxy-Hb may then be compared to determine a state of anesthesia. The effect of artifacts (e.g., strong surgery room lighting, patient-table tilting, patient intubation/extubation) on the fNIR signal may be removed using a noise removal algorithm. In selecting the noise removal algorithm, a switching technique may be used to select the component analysis algorithm, such as a principal component analysis (PCA), an independent component analysis (ICA), or the like.


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