The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8798394 B1

PDF
Full Text
Expired
Date of Patent:
Aug. 05, 2014

Filed:

Apr. 24, 2012
Applicants:

G. Scott Lett, Hightstown, NJ (US);

Ned C. Haubein, Yardley, PA (US);

Gary Pestano, Lafayette, CO (US);

Inventors:

G. Scott Lett, Hightstown, NJ (US);

Ned C. Haubein, Yardley, PA (US);

Gary Pestano, Lafayette, CO (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06K 9/20 (2006.01); G06K 9/00 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6428 (2013.01); G01N 2021/6423 (2013.01); G01N 21/6458 (2013.01); G01N 2021/6439 (2013.01); G01N 2021/6421 (2013.01);
Abstract

A biological sample such as a tissue section is stained with one or more quantum dots and possibly other fluorophores (total number of fluorophores N). A camera coupled to a microscope generates an image of the specimen at a plurality of different wavelengths within the emission spectral band of the N fluorophores. An analysis module calculates coefficients C1 . . . CN at each pixel which are related to the concentration of each of the individual fluorophores. Morphological processing instructions find biological structures. A display module displays quantitative analysis results to the user. The quantitative analysis display includes histograms of the biological structures, scatter plots of fluorophore concentrations, statistical data, spectral data, image data and still others.


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