The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2014
Filed:
Oct. 16, 2008
M. Arshad Siddiqui, Newton, MA (US);
Chaoyang Dai, Acton, MA (US);
Umar Faruk Mansoor, Framingham, MA (US);
Liping Yang, Arlington, MA (US);
Lalalnthi Dilrukshi Vitharana, Somerville, MA (US);
Angie R. Angeles, Boston, MA (US);
M. Arshad Siddiqui, Newton, MA (US);
Chaoyang Dai, Acton, MA (US);
Umar Faruk Mansoor, Framingham, MA (US);
Liping Yang, Arlington, MA (US);
Lalalnthi Dilrukshi Vitharana, Somerville, MA (US);
Angie R. Angeles, Boston, MA (US);
Mercky Sharp & Dohme Corp., Rahway, NY (US);
Abstract
The present invention relates to compounds of Formula (I), below, (wherein X, R1, R2, R3, p, E, ring A, and ring B are as defined herein). The present invention also relates to compositions (including pharmaceutically acceptable compositions) comprising these compounds, alone and in combination with one or more additional therapeutic agents, and to methods for their use in inhibiting KSP kinesin activity, and for treating cellular proliferative diseases or disorders associated with KSP kinesin activity. Formula I