The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2014
Filed:
Apr. 19, 2004
Applicants:
Anna Maria Caccuri, Rome, IT;
Giorgio Ricci, Rome, IT;
Inventors:
Anna Maria Caccuri, Rome, IT;
Giorgio Ricci, Rome, IT;
Assignee:
Universita Degli Studi di Roma “Tor Vergata”, Rome, IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/82 (2006.01); A61K 31/41 (2006.01); A61K 45/06 (2006.01); A61K 31/4245 (2006.01);
U.S. Cl.
CPC ...
A61K 45/06 (2013.01); A61K 31/4245 (2013.01);
Abstract
Derivatives of the heterocyclic compound known as 7-nitro-benzofurazan or 7-nitro-2,1,3-benzoxadiazole, are agents having a strong inhibiting activity towards members of the glutathione S-transferase (GST) superfamily that are hyperexpressed in cancer cells, and make them particularly resistant to many stress factors. These compounds are useful in the production of pharmaceutical drugs to be used in anticancer therapy, and may be employed either alone or in combination with other chemotherapeutic agents.