The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2014

Filed:

Aug. 11, 2011
Applicants:

Brian S. Freeze, Boston, MA (US);

Masaaki Hirose, Kanagawa, JP;

Yongbo HU, Winchester, MA (US);

Todd B. Sells, Bellingham, MA (US);

Zhan Shi, Concord, MA (US);

Stepan Vyskocil, Arlington, MA (US);

Tianlin Xu, Shrewsbury, MA (US);

Inventors:

Brian S. Freeze, Boston, MA (US);

Masaaki Hirose, Kanagawa, JP;

Yongbo Hu, Winchester, MA (US);

Todd B. Sells, Bellingham, MA (US);

Zhan Shi, Concord, MA (US);

Stepan Vyskocil, Arlington, MA (US);

Tianlin Xu, Shrewsbury, MA (US);

Assignee:

Millennium Pharmaceuticals, Inc., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); C07D 413/04 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides compounds of formula IA-i-a or IB-i-a and subsets thereof: wherein Z, HY, R, R, R, G, W, n, and A and subsets thereof are as described in the specification. The compounds are inhibitors of PI3K and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.


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