The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2014
Filed:
Jun. 01, 2007
Hiroki Fujieda, Kobe, JP;
Hironori Otsu, Matsubara, JP;
Shoji Yasufuku, Otsu, JP;
Masaaki Shirai, Kyoto, JP;
Hiroki Fujieda, Kobe, JP;
Hironori Otsu, Matsubara, JP;
Shoji Yasufuku, Otsu, JP;
Masaaki Shirai, Kyoto, JP;
Nippon Shinyaku Co., Ltd., Kyoto, JP;
Abstract
A main object of the invention is to provide a novel useful vitamin Dderivative, which has an excellent vitamin Dactivity and, as compared with conventional vitamin Dderivatives, has a relatively small amount of influence on the systemic calcium metabolism. The invention includes a 9,10-secopregnane derivative of the following general formula [1] and a pharmaceutical composition containing it as active ingredient. In the general formula [1], the following partial structure between the 16-position and the 17-position means a single bond or a double bond: Y is a single bond, an alkylene, an alkenylene or phenylene; Rand Rare the same or different, each represents hydrogen, an alkyl or a cycloalkyl; or Rand R, taken together with the adjacent carbon atom, form a cycloalkyl; Ris hydrogen or methyl; Z is hydrogen, hydroxy or —NRR.