The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2014
Filed:
Aug. 31, 2011
Applicants:
Geert-jan Boons, Athens, GA (US);
Jun Guo, Athens, GA (US);
Inventors:
Geert-Jan Boons, Athens, GA (US);
Jun Guo, Athens, GA (US);
Assignee:
University of Georgia Research Foundation, Inc., Athens, GA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/00 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48138 (2013.01);
Abstract
Compounds and methods for use in selectively inhibiting a lytic enzyme based on feedback inhibition are described. The conjugated compound serves as a substrate for a lytic enzyme. Cleavage of the conjugated compound by the lytic enzyme releases an inhibitor of the enzyme.