The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2014
Filed:
Aug. 02, 2011
Jan Wim Vrijbloed, Zürich, CH;
Daniel Obrecht, Blättwil, CN;
Sergio Locurio, Küsnacht, CH;
Frank Otto Gombert, Huttingen, DE;
Christian Ludin, Aesch, CH;
Françoise Jung, Zürich, CH;
Jan Wim Vrijbloed, Zürich, CH;
Daniel Obrecht, Blättwil, CN;
Sergio Locurio, Küsnacht, CH;
Frank Otto Gombert, Huttingen, DE;
Christian Ludin, Aesch, CH;
Françoise Jung, Zürich, CH;
Polyphor Ltd., Allschwil, CH;
Universität Zürich, Zürich, CH;
Abstract
A method of screening for template-fixed β-hairpin mimetics and libraries including a plurality of these mimetics is provided. The template-fixed β-hairpin mimetics are of the following general formula:R-Cys-Z-Cys-R  Iwherein the two cysteine residues are bridged by a disulfide bond, thereby forming a cyclic peptide; Rand Rare di- or tripeptide moieties of certain types, as defined herein; and Z is a chain of n amino acid residues with n being an integer from 4 to 20 and with each of these n amino acid residues being, independently, derived from any naturally occurring L-α-amino acid.