The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 05, 2014
Filed:
Feb. 18, 2009
Applicants:
Friedrich Scheiflinger, Vienna, AT;
Barbara Plaimauer, Vienna, AT;
Gerhard Antoine, Gross Enzersdorf, AT;
Inventors:
Friedrich Scheiflinger, Vienna, AT;
Barbara Plaimauer, Vienna, AT;
Gerhard Antoine, Gross Enzersdorf, AT;
Assignees:
Baxter International Inc., Deerfield, IL (US);
Baxter Healthcare SA, Glattpark (Opfikon), CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/07 (2010.01); C12N 5/16 (2006.01); C12N 7/02 (2006.01); C12N 11/00 (2006.01); C12N 13/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
This invention relates to adsorbents and methods for highly selective removal of anti-von Willebrand Factor-cleaving protease antibodies ('anti-vWF-cp-abs') from human plasma using human von Willebrand Factor-cleaving protease ('hvWF-cp') or fragments thereof as affinity ligands. The adsorbents can be used for treating disorders associated with the occurrence of anti-vWF-cp-abs in patients, such as thromboembolic diseases.