The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2014

Filed:

May. 03, 2011
Applicants:

Ka-yiu San, Houston, TX (US);

George Bennett, Houston, TX (US);

Grant Balzer, Houston, TX (US);

Jiangfeng Zhu, Houston, TX (US);

Chandresh Thakker, Houston, TX (US);

Ailen Sanchez, Foster City, CA (US);

Inventors:

Ka-Yiu San, Houston, TX (US);

George Bennett, Houston, TX (US);

Grant Balzer, Houston, TX (US);

Jiangfeng Zhu, Houston, TX (US);

Chandresh Thakker, Houston, TX (US);

Ailen Sanchez, Foster City, CA (US);

Assignee:

William Marsh Rice University, Houston, TX (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/70 (2006.01);
U.S. Cl.
CPC ...
Abstract

Improved bacteria for making succinate and other 4 carbon dicarboxylates from the Krebs cycle have modifications to reduce acetate, lactate, EtOH and formate, as well as turn on the glyoxylate shunt, produce more NADH and overexpress In one embodiment, the bacteria are ΔadhEΔldhAΔiclRΔack-pta plus PYCand NAD-dependant FDH.


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