The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2014

Filed:

Nov. 25, 2011
Applicants:

William D. Arnold, San Diego, CA (US);

Christelle Jost, San Diego, CA (US);

Brian Noland, Temecula, CA (US);

Jonathan Gary, San Diego, CA (US);

Joseph Buechler, Carlsbad, CA (US);

Vance Wong, Cardiff, CA (US);

Scott Harold Rongey, San Diego, CA (US);

Uday Kumar Veeramallu, San Diego, CA (US);

Kelline Marie Rodems, Oceanside, CA (US);

Inventors:

William D. Arnold, San Diego, CA (US);

Christelle Jost, San Diego, CA (US);

Brian Noland, Temecula, CA (US);

Jonathan Gary, San Diego, CA (US);

Joseph Buechler, Carlsbad, CA (US);

Vance Wong, Cardiff, CA (US);

Scott Harold Rongey, San Diego, CA (US);

Uday Kumar Veeramallu, San Diego, CA (US);

Kelline Marie Rodems, Oceanside, CA (US);

Assignee:

Alere San Diego, Inc., San Diego, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 31/00 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates in part to diagnosing the occurrence of heart failure, particularly in subjects who exhibit a normal body fluid level of a natriuretic peptide. The present invention further relates in part to assigning an outcome risk (e.g., worsening cardiac function or a mortality risk, a risk of rehospitalization) to a subject. The methods comprise performing one or more assays that detect one or more biomarkers selected from the group consisting of WAP4C, ESAM, LTBR, Mesothelin, and Syndecan-1 performed on a body fluid sample obtained from a subject, and assigning diagnosis or risk based, at least in part, on the result(s) obtained thereby.


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