The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2014

Filed:

Aug. 03, 2012
Applicants:

Hongjie Dai, Cupertino, CA (US);

Nadine Wong Shi Kam, Ann Arbor, MI (US);

Paul A. Wender, Menlo Park, CA (US);

Zhuang Liu, Stanford, CA (US);

Inventors:

Hongjie Dai, Cupertino, CA (US);

Nadine Wong Shi Kam, Ann Arbor, MI (US);

Paul A. Wender, Menlo Park, CA (US);

Zhuang Liu, Stanford, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/16 (2006.01); A61K 9/50 (2006.01); A61K 38/54 (2006.01); A61K 39/00 (2006.01); B82Y 5/00 (2011.01); C12N 15/11 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Methods and materials for delivering biologically active molecules to cells in vitro or in vivo are provided. The methods and materials use carbon nanotubes or other hydrophobic particles, tubes and wires, functionalized with a linking group that is covalently bound to the nanotubes, or, alternatively, to the biologically active molecule, such as a protein. The biologically active molecule is preferably released from the nanotube when the complex has been taken up in an endosome.


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