The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2014

Filed:

Sep. 16, 2011
Applicants:

Harald Arno Butterweck, Vienna, AT;

Bernhard Kölbl, Achau, AT;

Lucia Hofbauer, Eggenburg, AT;

Wolfgang Teschner, Vienna, AT;

Hans-peter Schwarz, Vienna, AT;

Inventors:

Harald Arno Butterweck, Vienna, AT;

Bernhard Kölbl, Achau, AT;

Lucia Hofbauer, Eggenburg, AT;

Wolfgang Teschner, Vienna, AT;

Hans-Peter Schwarz, Vienna, AT;

Assignees:

Baxter International Inc., Deerfield, IL (US);

Baxter Healthcare SA, Glattpark (Opfikon), unknown;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 47/02 (2006.01); A61K 47/18 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0019 (2013.01); A61K 47/02 (2013.01); A61K 47/183 (2013.01);
Abstract

The present invention provides, among other aspects, storage stabile aqueous formulations of immunoglobulins with histidine at a mildly acidic to neutral pH. The present invention also provides methods for stabilizing immunoglobulin compositions by formulating with histidine at a mildly acidic to neutral pH. Advantageously, the methods and formulations provided herein allow stabile aqueous compositions of immunoglobulins at mildly acidic to neutral pH useful for parenteral administration.


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