The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2014

Filed:

Aug. 28, 2009
Applicants:

Sultan Darvesh, Halifax, CA;

Eric Joy, Lower Sackville, CA;

Earl Martin, Halifax, CA;

Ian Macdonald, Dartmouth, CA;

Ian Pottie, Middle Sackville, CA;

Inventors:

Sultan Darvesh, Halifax, CA;

Eric Joy, Lower Sackville, CA;

Earl Martin, Halifax, CA;

Ian Macdonald, Dartmouth, CA;

Ian Pottie, Middle Sackville, CA;

Assignee:

Treventis Corporation, Bernville, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/04 (2006.01); A61K 31/54 (2006.01); B62B 3/02 (2006.01);
U.S. Cl.
CPC ...
B62B 3/022 (2013.01); B62B 2205/12 (2013.01); B62B 2202/404 (2013.01); B62B 2205/24 (2013.01);
Abstract

Compounds useful for the early diagnosis of malignant tumors, multiple sclerosis, and especially Alzheimer's Disease and related dementias; especially compounds of Formula (I) wherein Ris selected from the group consisting of hydrogen, cyano, fluoro, iodo, alkyl, and aryl; Ris selected from the group consisting of hydrogen, alkyl, and aryl; X is selected from the group consisting of CH, CHO, oxygen, OCH, CHS, SCH, NH, N-alkyl, and N-aryl; Y is an optional spacer group, absent or selected from the group consisting of oxygen, sulfur, NH, N-alkyl, and N-aryl; and Z is selected from the group consisting of alkyl substituted with cyano, fluoro, or iodo and aryl substituted with cyano, fluoro, or iodo. In a preferred embodiment, Rand Rare hydrogen, X is CHO, Y is absent, and Z is phenyl substituted with fluoro, cyano, or iodo. In some embodiments, Z is more specificallyF-phenyl orI-phenyl orI-phenyl. Other compounds are also provided.


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