The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 2014
Filed:
Nov. 04, 2010
Ivars Kalvins, Ikskile, LV;
Antons Lebedevs, Riga, LV;
Aleksandrs Cernobrovijs, Riga, LV;
Maija Dambrova, Riga, LV;
Liga Zvejniece, Marupe, LV;
Maksims Vorona, Riga, LV;
Grigorijs Veinbergs, Riga, LV;
Ivars Kalvins, Ikskile, LV;
Antons Lebedevs, Riga, LV;
Aleksandrs Cernobrovijs, Riga, LV;
Maija Dambrova, Riga, LV;
Liga Zvejniece, Marupe, LV;
Maksims Vorona, Riga, LV;
Grigorijs Veinbergs, Riga, LV;
JSC Grindeks, Riga, LV;
Abstract
The invention relates to the 5S,4R-enantiomer of 2-(5-methyl-2-oxo-4-phenyl-pyrrolidin-1-yl)-acetamide with cognition enhancing activity of high pharmacological value and to its preparation method which includes the synthesis of 5S-methyl-4R-phenylpyrrolidin-2-one, its N-alkylation with ethyl haloacetate and the treatment of intermediate ethyl 2-(5S-methyl-2-oxo-4R-phenyl-pyrrolidin-1-yl)-acetate with ammonia.