The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 2014
Filed:
Sep. 16, 2010
Gregor James Macdonald, Beerse, BE;
Johannes Wilhelmus John F. Thuring, Antwerp, BE;
Frans Alfons Maria Van Den Keybus, Beerse, BE;
Yves Emiel Maria Van Roosbroeck, Beerse, BE;
Gregor James Macdonald, Beerse, BE;
Johannes Wilhelmus John F. Thuring, Antwerp, BE;
Frans Alfons Maria Van den Keybus, Beerse, BE;
Yves Emiel Maria Van Roosbroeck, Beerse, BE;
Janssen Pharmaceutica NV, Beerse, BE;
Abstract
The present invention relates to N-phenyl-1-(4-pyridinyl)-1H-pyrazol-3-amine derivatives and pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to formula (I) Wherein R, R, R, R, R, Rhave the meaning defined in the claims. The invention particularly relates to positive allosteric modulators of nicotinic acetylcholine receptors, such positive allosteric modulator having the capability to increase the efficacy of nicotinic receptor agonists.