The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2014

Filed:

Mar. 30, 2012
Applicants:

Hariprasad Vankayalapati, Draper, UT (US);

Rajendra P Appalaneni, Stamford, CT (US);

Y. Vekata Krishna Reddy, Hyderabad, IN;

Inventors:

Hariprasad Vankayalapati, Draper, UT (US);

Rajendra P Appalaneni, Stamford, CT (US);

Y. Vekata Krishna Reddy, Hyderabad, IN;

Assignee:

Arrien Pharmaceuticals LLC, Somerset, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); A61K 31/497 (2006.01); C07D 401/04 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01);
Abstract

Substituted 5-(pyrazin-2-yl)-1H-pyrazolo[3,4-b]pyridine, 5-(pyrazin-2-yl)-1H-pyrrolo[2,3-b]pyridine and pyrazolo[3,4-b]pyridine derivatives according to formula I, II and VII, and methods for making same, which are inhibitors of constitutively activated Tyrosine Kinase-Like (TKL), CMGC protein kinases family members and can be useful in the treatment of Parkinson's disease, Alzheimer's disease, Down's Syndrome, Huntington's disease, other neurodegenerative and central nervous system disorders, cancer, metabolic disorders and inflammatory diseases. Also disclosed are pharmaceutical compositions including the compounds and methods of inhibiting wild type and/or mutated protein kinase activities of these families and the treatment of disorders associated therewith using compounds and pharmaceutical compositions including the compounds.


Find Patent Forward Citations

Vankayalapati, Hariprasad. (2014). [object object] (U.S. Patent No. 8791112). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8791112

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