The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2014

Filed:

Mar. 05, 2010
Applicants:

Gal Bitan, Los Angeles, CA (US);

Akila Shanmugam, Allen, TX (US);

Aleksey Lomakin, Swampscott, MA (US);

Thomas Schrader, Mettmann, DE;

Frank Gerrit Klarner, Bochum, DE;

Peter Talbiersky, Krems, AT;

Jolanta Polkowska, Essen, DE;

Frank Bastkowski, Braunschweig, DE;

Sharmistha Sinha, Ames, IA (US);

Sally Frautschy, Santa Monica, CA (US);

Inventors:

Gal Bitan, Los Angeles, CA (US);

Akila Shanmugam, Allen, TX (US);

Aleksey Lomakin, Swampscott, MA (US);

Thomas Schrader, Mettmann, DE;

Frank Gerrit Klarner, Bochum, DE;

Peter Talbiersky, Krems, AT;

Jolanta Polkowska, Essen, DE;

Frank Bastkowski, Braunschweig, DE;

Sharmistha Sinha, Ames, IA (US);

Sally Frautschy, Santa Monica, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/6615 (2006.01); A61K 31/663 (2006.01); C07K 14/47 (2006.01); C07F 9/40 (2006.01); C07F 9/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides novel compositions to inhibit the aggregation of amyloid proteins. In various embodiments the compositions comprise a molecular tweezers that binds lysine and/or arginine and thereby inhibits the aggregation of amyloidogenic proteins.


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