The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 2014
Filed:
Aug. 03, 2012
C. Frank Bennett, Carlsbad, CA (US);
Kenneth W. Dobie, Del Mar, CA (US);
Susan M. Freier, San Diego, CA (US);
Stanley T. Crooke, Carlsbad, CA (US);
C. Frank Bennett, Carlsbad, CA (US);
Kenneth W. Dobie, Del Mar, CA (US);
Susan M. Freier, San Diego, CA (US);
Stanley T. Crooke, Carlsbad, CA (US);
Isis Pharmaceuticals, Inc., Carlsbad, CA (US);
Abstract
Disclosed herein are compounds, compositions and methods for modulating the expression of LMNA in a cell, tissue or animal. Also provided are methods of target validation. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders. Further provided are methods of identifying cis splicing regulatory elements of a selected mRNA using the disclosed compounds.