The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 2014
Filed:
Sep. 26, 2003
Soren Flygenring Christensen, Frederiksberg, DK;
Jens Hog Truelsen, Elsinore, DK;
Morten Meldal, Copenhagen, DK;
Roice Michael, Frederiksberg, DK;
Ib Johannsen, Vaerlose, DK;
Soren Flygenring Christensen, Frederiksberg, DK;
Jens Hog Truelsen, Elsinore, DK;
Morten Meldal, Copenhagen, DK;
Roice Michael, Frederiksberg, DK;
Ib Johannsen, Vaerlose, DK;
MPM-Holding APS, Copenhagen, DK;
Abstract
The invention relates to a spatially encoded polymer matrix in the form of a bead or a granule for combinatorial solid phase synthesis, assaying, functional proteomics and diagnostic use. Compositions of such beads or granules are also provided. Each beaded polymer matrix of the composition comprises a plurality of spatially immobilized particles. The spatial immobilization of the particles confers on each beaded polymer matrix a 'fingerprint' which enables identification of unique beads in a population of beads. The unique identification of individual beads makes it possible to perform combinatorial chemistry strategies while logging individual chemical transformation. Also provided are methods for detection of relative positions in space of particles, methods for generating matrices, methods for distance matrix determination, methods for identifying individual matrices and devices for recording and storing images of matrices.