The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2014

Filed:

Sep. 17, 2010
Applicant:

J. Gregory Zeikus, Okemos, MI (US);

Inventor:

J. Gregory Zeikus, Okemos, MI (US);

Assignee:

PBS Biotech, Inc., Camarillo, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/12 (2006.01); A01G 7/00 (2006.01); C12M 1/02 (2006.01); B01F 7/04 (2006.01); C12M 1/00 (2006.01); B01F 7/22 (2006.01); C12M 1/12 (2006.01); B01F 7/00 (2006.01); C12M 1/09 (2006.01); C12M 1/06 (2006.01); C12M 1/34 (2006.01); B01F 3/04 (2006.01);
U.S. Cl.
CPC ...
C12M 41/42 (2013.01); C12M 27/00 (2013.01); B01F 2003/04631 (2013.01); B01F 7/04 (2013.01); C12M 23/28 (2013.01); B01F 2003/04673 (2013.01); B01F 7/22 (2013.01); B01F 3/04531 (2013.01); C12M 37/00 (2013.01); B01F 7/00916 (2013.01); C12M 23/56 (2013.01); B01F 7/00183 (2013.01); C12M 27/06 (2013.01); B01F 7/00308 (2013.01);
Abstract

A pneumatic bioreactor includes a vessel containing a fluid to be mixed and at least one mixing device driven by gas pressure. A first embodiment includes a floating impeller that rises and falls in the fluid as gas bubbles carry it upward to the surface where the gas is then vented, permitting the impeller to sink in the fluid. The floating impeller may be tethered to a second impeller with a flexible member and pulley. The mixing speed is controlled with electromagnets in the vessel acting upon magnetic material in the impeller or its guides. In another embodiment, floating pistons mix the fluid, pushing it through a mixing plate with one or more apertures. In a third embodiment, the mixing device is a rotating drum with bubble-catching blades and rotating mixing plates with apertures. The top of the vessel for these mixers may include a closed top and sterile filters.


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