The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 2014
Filed:
Jan. 19, 2010
Applicant:
Khalid S. Khabar, Riyadh, SA;
Inventor:
Khalid S. Khabar, Riyadh, SA;
Assignees:
King Faisal Specialist Hospital & Research Centre, Riyadh, SA;
Terramark Markencreation GmbH, Bremen, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to a method for increasing the expression of a protein in cells, preferably in eukaryotic cells, by reducing the number of RNase L cleavage sites in the coding and/or non-coding region of the nucleic acid sequence of said protein. Furthermore, it relates to nucleic acid sequences exhibiting a reduced number of RNase L cleavage sites as well as to the proteins translated from such sequences.