The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 2014
Filed:
Apr. 24, 2008
Fabrice Agou, Paris, FR;
Gilles Courtois, Paris, FR;
Alain Israel, Paris, FR;
Michel Vernon, Paris, FR;
Francois Traincard, Issy-les-Moulineaux, FR;
Shoji Yamaoka, Tokyo, JP;
Fabrice Agou, Paris, FR;
Gilles Courtois, Paris, FR;
Alain Israel, Paris, FR;
Michel Vernon, Paris, FR;
Francois Traincard, Issy-les-Moulineaux, FR;
Shoji Yamaoka, Tokyo, JP;
Institut Pasteur, Paris, FR;
Abstract
The present invention relates to polypeptides that inhibit the NF-κB signaling pathway and polynucleotides encoding the same. The present invention further provides methods for the modulation of and/or treatment of inflammatory responses, oncogenesis, viral infection; the regulation of cell proliferation and apoptosis; and regulation of B or T lymphocytes in antigenic stimulation, by administering the polypeptides of the present invention to a subject in need thereof. Finally, the present invention provides a method of identifying polypeptides that modulate oligomerization of NEMO.