The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2014

Filed:

Mar. 11, 2011
Applicants:

Michael B. Chancellor, Pittsburgh, PA (US);

Johnny Huard, Wexford, PA (US);

Christopher Capelli, Kenosha, WI (US);

Steve Chung, Pittsburgh, PA (US);

Michael S. Sacks, Pittsburgh, PA (US);

Inventors:

Michael B. Chancellor, Pittsburgh, PA (US);

Johnny Huard, Wexford, PA (US);

Christopher Capelli, Kenosha, WI (US);

Steve Chung, Pittsburgh, PA (US);

Michael S. Sacks, Pittsburgh, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/00 (2006.01); A61F 13/00 (2006.01); A61L 27/36 (2006.01); A61L 27/38 (2006.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
A61L 27/3679 (2013.01); A61L 27/3834 (2013.01); A61L 27/3629 (2013.01); C12N 5/0668 (2013.01); C12N 5/0658 (2013.01);
Abstract

A rapid method for preparing stem cell and physiologically acceptable matrix compositions for use in tissue and organ repair is described. Compared with previous tissue engineering materials, the stem cell-matrix compositions of the present invention do not require long-term incubation or cultivation in vitro prior to use in in vivo applications. The stem cells can be from numerous sources and may be homogeneous, heterogeneous, autologous, and/or allogeneic in the matrix material. The stem cell-matrix compositions provide point of service utility for the practitioner, wherein the stem cells and matrix can be combined not long before use, thereby alleviating costly and lengthy manufacturing procedures. In addition, the stem cells offer unique structural properties to the matrix composition which improves outcome and healing after use. Use of stem cells obtained from muscle affords contractility to the matrix composition.


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