The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2014

Filed:

Sep. 02, 2009
Applicants:

Bruno Pitard, Reze, FR;

Charles Tellier, Notre Dame des Landes, FR;

Corinne Miral, Treillieres, FR;

Emilie Letrou-bonneval, Limoges, FR;

Inventors:

Bruno Pitard, Reze, FR;

Charles Tellier, Notre Dame des Landes, FR;

Corinne Miral, Treillieres, FR;

Emilie Letrou-Bonneval, Limoges, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0041 (2013.01);
Abstract

A stabilized multimodular assembly for intracellular delivery comprising a complex of at least one cationic transfection agent and of at least one negatively charged macromolecule, wherein the complex has a theoretical charge ratio ranging from about 0 to about 4, and an efficient amount of at least one amphiphilic block co-polymer acting as a steric colloidal stabilizer with respect to the complex, the block co-polymer having hydrophilic and hydrophobic blocks wherein at least one hydrophilic block is conjugated with at least one targeting ligand.


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