The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 2014
Filed:
Mar. 12, 2012
Brad J. Spellberg, Rancho Palos Verdes, CA (US);
Ashraf S. Ibrahim, Irvine, CA (US);
John E Edwards, Jr., Palos Verdes Estates, CA (US);
Brad J. Spellberg, Rancho Palos Verdes, CA (US);
Ashraf S. Ibrahim, Irvine, CA (US);
John E Edwards, Jr., Palos Verdes Estates, CA (US);
Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA (US);
Abstract
The invention is based, in part, on the discovery of a novel cell-based immunotherapy that can recapitulate neutrophil functions in neutropenic individuals afflicted with a microbial infection. The therapeutic methods of the invention are broadly applicable to treat any infection in a neutropenic individual, including infections caused by bacteria, fungi, protozoa, and viruses. The methods of the invention represent a practical, rapid cell-based immunotherapy for refractory infections comprising compositions of activated, irradiated HL-60 cells.