The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 2014
Filed:
May. 15, 2012
Joel Tocker, Narberth, PA (US);
Jacques J. Peschon, Seattle, WA (US);
David Fitzpatrick, Karana Downs, AU;
James F. Smothers, Quincy, MA (US);
Christopher Mehlin, Seattle, WA (US);
Ai Ching Lim, Mercer Island, WA (US);
Joel Tocker, Narberth, PA (US);
Jacques J. Peschon, Seattle, WA (US);
David Fitzpatrick, Karana Downs, AU;
James F. Smothers, Quincy, MA (US);
Christopher Mehlin, Seattle, WA (US);
Ai Ching Lim, Mercer Island, WA (US);
Amgen Inc., Thousand Oaks, CA (US);
Abstract
The present invention relates to IL-17 Receptor A (IL-17RA or IL-17R) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by IL-17 Receptor A activation by one or more IL-17 ligands. The present invention relates to the identification of neutralizing determinants on IL-17 Receptor A (IL-17RA or IL-17R) and antibodies that bind thereto. Aspects of the invention also include antibodies that compete for binding with the IL-17RA neutralizing antibodies described herein.