The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 2014
Filed:
Mar. 26, 2010
Harry John Wadsworth, Amersham, GB;
BO Shan, Jiangsu, CN;
Dennis O'shea, Amersham, GB;
Joanna Marie Passmore, Amersham, GB;
William John Trigg, Amersham, GB;
Amanda Ewan, Amersham, GB;
Harry John Wadsworth, Amersham, GB;
Bo Shan, Jiangsu, CN;
Dennis O'Shea, Amersham, GB;
Joanna Marie Passmore, Amersham, GB;
William John Trigg, Amersham, GB;
Amanda Ewan, Amersham, GB;
GE Healthcare Limited, Buckinghamshire, GB;
Abstract
An indole-based in vivo imaging agent is provided by the present invention that binds with high affinity to PBR, has good uptake into the brain following administration, and which has good selective binding to PBR. The invention also includes a precursor compound useful in the synthesis of the in vivo imaging agent of the invention, as well as a method for synthesis of said in vivo imaging agent comprising use of said precursor compound, and a kit for carrying out said method. Also provided is a cassette for automated synthesis of the in vivo imaging agent. Further aspects of the invention include a radiopharmaceutical composition comprising the in vivo imaging agent of the invention, and methods for the use of said in vivo imaging agent.