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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8785635 B1

PDFFull Text
Date of Patent:
Jul. 22, 2014

Filed:

Aug. 27, 2008

Cyclopamine analogs

Applicants:

Brian Austad, Tewksbury, MA (US);

Mark L. Behnke, Somerville, MA (US);

Alfredo C. Castro, Winchester, MA (US);

Michael J. Grogan, Winchester, MA (US);

Somarajannair Janardanannair, Woburn, MA (US);

Andre Lescarbeau, Somerville, MA (US);

Stephane Peluso, Somerville, MA (US);

Martin Tremblay, Melrose, MA (US);

Inventors:

Brian Austad, Tewksbury, MA (US);

Mark L. Behnke, Somerville, MA (US);

Alfredo C. Castro, Winchester, MA (US);

Michael J. Grogan, Winchester, MA (US);

Somarajannair Janardanannair, Woburn, MA (US);

Andre Lescarbeau, Somerville, MA (US);

Stephane Peluso, Somerville, MA (US);

Martin Tremblay, Melrose, MA (US);

Assignee:

Infinity Pharmaceuticals, Inc., Cambridge, MA (US);

Attorney:

Fish & Richardson P.C.

Primary Examiner:

Andrew D Kosar

Assistant Examiner:

Raymond Covington

Int. Cl.
CPC ...
C07D 211/00 (2006.01); C07D 401/00 (2006.01); C07D 491/02 (2006.01); A61K 31/196 (2006.01); A61K 45/06 (2006.01); A61K 31/4355 (2006.01); C07D 491/04 (2006.01); A61K 31/198 (2006.01); A61K 31/704 (2006.01); A61K 31/664 (2006.01); A61K 38/21 (2006.01); A61K 31/7076 (2006.01); C07D 491/107 (2006.01); A61K 31/58 (2006.01); A61K 31/17 (2006.01); A61K 31/4745 (2006.01); A61K 31/573 (2006.01); A61K 31/454 (2006.01); A61K 31/56 (2006.01); C07D 491/10 (2006.01); C07J 69/00 (2006.01); C07D 491/048 (2006.01); A61K 31/69 (2006.01); A61K 31/519 (2006.01); A61K 31/7068 (2006.01);
U.S. Cl.
CPC ...
C07D 491/048 (2013.01); A61K 31/196 (2013.01); A61K 45/06 (2013.01); A61K 31/4355 (2013.01); C07D 491/04 (2013.01); A61K 31/198 (2013.01); A61K 31/704 (2013.01); A61K 31/664 (2013.01); A61K 38/21 (2013.01); A61K 31/7076 (2013.01); C07D 491/107 (2013.01); A61K 31/58 (2013.01); A61K 31/17 (2013.01); A61K 31/4745 (2013.01); A61K 31/573 (2013.01); A61K 31/454 (2013.01); A61K 31/56 (2013.01); C07D 491/10 (2013.01); C07J 69/00 (2013.01); A61K 31/69 (2013.01); A61K 31/519 (2013.01); A61K 31/7068 (2013.01);
Abstract

The invention provides novel derivatives of cyclopamine having the following formula:

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