The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 22, 2014
Filed:
Jun. 20, 2012
Applicants:
Günther Bernhardt, Regensburg, DE;
Miriam Ertel, Munich, DE;
Armin Buschauer, Regensburg, DE;
Jörg Nink, Holzkirchen, DE;
Inventors:
Günther Bernhardt, Regensburg, DE;
Miriam Ertel, Munich, DE;
Armin Buschauer, Regensburg, DE;
Jörg Nink, Holzkirchen, DE;
Assignee:
Hexal AG, Holzkirchen, DE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/551 (2006.01); A61K 9/70 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to diester prodrugs of cilazaprilate which undergo enzymatic cleavage to release the active metabolite cilazaprilate that is used for the treatment of hypertension and congestive heart failure. Furthermore the diester prodrugs of cilazaprilate possess all the properties necessary to be topically administered, preferably via transdermal therapeutic systems.