The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 22, 2014

Filed:

Nov. 13, 2012
Applicants:

Cook Medical Technologies Llc, Bloomington, IN (US);

Cook Biotech Incorporated, West Lafayette, IN (US);

Inventors:

Laura-Lee Farrell, Maplewood, MN (US);

Chad E. Johnson, West Lafayette, IN (US);

Assignees:

Cook Medical Technologies LLC, Bloomington, IN (US);

Cook Biotech Incorporated, West Lafayette, IN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 38/39 (2006.01); A61K 9/14 (2006.01); A61P 17/02 (2006.01); B29C 41/04 (2006.01); B29C 39/08 (2006.01); A61L 27/36 (2006.01); B29C 67/20 (2006.01); A61L 31/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0087 (2013.01); A61L 27/3633 (2013.01); B29C 67/20 (2013.01); A61L 31/005 (2013.01); A61K 38/39 (2013.01); B29C 39/08 (2013.01);
Abstract

A method for forming an extracellular matrix material (ECM) material includes providing at least an ECM composition containing ECM particles varying in their capacity for migration through a fluid medium, including at least one population of expanded ECM particles. The ECM composition is combined in a fluid medium to form a flowable ECM composition. The flowable ECM composition is subjected to a centrifugal force in a mold for a period of time sufficient to distribute the ECM particles according to differences in their physical characteristics. The ECM composition is dried to form a dried ECM material having a density gradient extending from a less dense region to a more dense region. The dried ECM material may formed as a porous, substantially acellular ECM material expandable in an aqueous fluid environment by at least 100% in volume.


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