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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8784862 B1

PDFFull Text
Date of Patent:
Jul. 22, 2014

Filed:

Jun. 30, 2010

Compounds and method for coating surfaces in a hemocompatible manner

Applicants:

Roland Horres, Stolberg, DE;

Marita Katharina Linssen, Gòttingen, DE;

Michael Hoffmann, Eschweiler, DE;

Erika Hoffmann, Eschweiler, DE;

Donate Dibiase, Aachen, DE;

Volker Faust, Aachen, DE;

Inventors:

Roland Horres, Stolberg, DE;

Marita Katharina Linssen, Gòttingen, DE;

Michael Hoffmann, Eschweiler, DE;

Erika Hoffmann, Eschweiler, DE;

Donate DiBiase, Aachen, DE;

Volker Faust, Aachen, DE;

Assignee:

Hemoteq AG, Würselen, DE;

Attorneys:

Meyertons, Hood, Kivlin, Kowert & Goetzel, P.C.

Eric B. Meyertons

Primary Examiner:

Richard Schnizer

Assistant Examiner:

Alma Pipic

Int. Cl.
CPC ...
A61F 2/82 (2013.01); A61K 31/337 (2006.01); A61K 31/436 (2006.01); A61K 9/00 (2006.01); A61P 29/00 (2006.01); A61L 31/10 (2006.01); C08L 5/10 (2006.01); A61L 33/08 (2006.01); A61L 31/16 (2006.01); A61K 31/722 (2006.01); A61K 31/727 (2006.01); A61K 31/095 (2006.01); A61K 31/045 (2006.01); A61K 31/075 (2006.01); A61K 31/11 (2006.01); A61K 31/12 (2006.01); A61K 31/28 (2006.01); A61K 31/33 (2006.01); A61K 31/21 (2006.01); A61K 31/13 (2006.01);
U.S. Cl.
CPC ...
A61L 31/10 (2013.01); C08L 5/10 (2013.01); A61L 33/08 (2013.01); A61L 31/16 (2013.01); A61K 31/722 (2013.01); A61K 31/727 (2013.01); A61K 31/095 (2013.01); A61K 31/045 (2013.01); A61K 31/075 (2013.01); A61K 31/11 (2013.01); A61K 31/12 (2013.01); A61K 31/28 (2013.01); A61K 31/33 (2013.01); A61K 31/21 (2013.01); A61K 31/13 (2013.01);
Abstract

The invention concerns oligosaccharides and polysaccharides as well as the use of these oligosaccharides and/or polysaccharides, which contain the sugar unit N-acylglucosamine or N-acylgalactosamine for the production of hemocompatible surfaces as well as methods for the hemocompatible coating of surfaces with said oligosaccharides and/or polysaccharides, which imitate the common biosynthetic precursor substance of heparin, heparan sulphates and chitosan. The invention further describes methods for producing said oligosaccharides and/or polysaccharides and discloses various possibilities of using hemocompatibly coated surfaces. The invention relates particularly to the use of said oligosaccharides and/or polysaccharides on stents with at least one according to invention deposited hemocompatible coating, which contains an antiproliferative, antiinflammatory and/or antithrombotic active agent, methods for the preparation of said stents as well as the use of said stents for the prevention of restenosis.

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