The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 2014

Filed:

May. 26, 2010
Applicants:

Thomas Piccariello, Blacksburg, VA (US);

John D. Price, Blacksburg, VA (US);

Robert A. Oberlender, Blacksburg, VA (US);

Michaela E. Mulhare, Christiansburg, VA (US);

Mary C. Spencer, Blacksburg, VA (US);

Scott B. Palmer, Wilmette, IL (US);

Inventors:

Thomas Piccariello, Blacksburg, VA (US);

John D. Price, Blacksburg, VA (US);

Robert A. Oberlender, Blacksburg, VA (US);

Michaela E. Mulhare, Christiansburg, VA (US);

Mary C. Spencer, Blacksburg, VA (US);

Scott B. Palmer, Wilmette, IL (US);

Assignee:

Synthonics, Inc., Blacksburg, VA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07F 15/00 (2006.01); C07F 5/00 (2006.01); A61K 31/28 (2006.01); C07C 259/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

A coordination complex having a physiologically acceptable pKincludes a metal and a biologically active agent. The pKof the coordination complex is less than the pKof the biologically active agent. A pharmaceutical solution for treating a patient includes a coordination complex and water, wherein the coordination complex is at least partially soluble in the water at physiological pH and in a therapeutically efficacious concentration. A method for treating a patient includes administering a pharmaceutical solution including a coordination complex and water to a patient in need of a biologically active agent.


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