The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2014
Filed:
May. 08, 2009
Applicants:
Johannes Wilhelmus John F. Thuring, Antwerp, BE;
Gregor James Macdonald, Zoersel, BE;
Wei Zhuang, Antwerp, BE;
Inventors:
Johannes Wilhelmus John F. Thuring, Antwerp, BE;
Gregor James MacDonald, Zoersel, BE;
Wei Zhuang, Antwerp, BE;
Assignee:
Janssen Pharmaceutica NV, Beerse, BE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4155 (2006.01); A01N 43/36 (2006.01); C07D 231/02 (2006.01); C07D 401/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to 1-alkyl-3-aniline-5-aryl-pyrazole derivatives and pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to Formula (I). The invention particularly relates to positive allosteric modulators of nicotinic acetylcholine receptors, such positive allosteric modulator having the capability to increase the efficacy of nicotinic receptor agonists.