The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 2014
Filed:
Jun. 22, 2011
Takashi Kikuchi, Tokyo, JP;
Katsuhiko Gato, Tokyo, JP;
Koichiro Mukoyoshi, Tokyo, JP;
Tsuyoshi Kitamura, Tokyo, JP;
Takeshi Kawakami, Tokyo, JP;
Hironobu Yasuda, Ibaraki, JP;
Takashi Kikuchi, Tokyo, JP;
Katsuhiko Gato, Tokyo, JP;
Koichiro Mukoyoshi, Tokyo, JP;
Tsuyoshi Kitamura, Tokyo, JP;
Takeshi Kawakami, Tokyo, JP;
Hironobu Yasuda, Ibaraki, JP;
Astellas Pharma Inc., Tokyo, JP;
Abstract
[Problem] A salt or crystal of a compound which is highly stable in a solid state and useful as a bulk material for the preparation of a pharmaceutical product is provided. [Means for Solution] 4-{[(1R,2s,3S,5s,7s)-5-Hydroxy-2-adamantyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide succinate, 4-{[(1R,2s,3S,5s,7s)-5-hydroxy-2-adamantyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide hydrobromide, and 4-{[(1R,2s,3S,5s,7s)-5-hydroxy-2-adamantyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide hydrochloride and crystals thereof are useful as a bulk material for the preparation of a solid preparation, in particular, a solid dispersion preparation. Furthermore, the crystal of the hydrobromide has excellent stability in a solid state and is useful as a bulk material for the preparation of a pharmaceutical product.