IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8779089 B1

PDFFull Text
Date of Patent:
Jul. 15, 2014

Filed:

Nov. 18, 2010

Methods and compositions for soft tissue repair

Applicants:

Isaac Gilliam Sanford, Durham, NC (US);

Michelle Steffen Jansen, Durham, NC (US);

Paul Theodore Hamilton, Cary, NC (US);

Jonathan Allen Hodges, Durham, NC (US);

Shrikumar Ambujakshan Nair, Cary, NC (US);

Yuchen Chen, Chapel Hill, NC (US);

Martyn Kerry Darby, Chapel Hill, NC (US);

Hanne Gron, Durham, NC (US);

Ganesan Sathya, Cary, NC (US);

Inventors:

Isaac Gilliam Sanford, Durham, NC (US);

Michelle Steffen Jansen, Durham, NC (US);

Paul Theodore Hamilton, Cary, NC (US);

Jonathan Allen Hodges, Durham, NC (US);

Shrikumar Ambujakshan Nair, Cary, NC (US);

Yuchen Chen, Chapel Hill, NC (US);

Martyn Kerry Darby, Chapel Hill, NC (US);

Hanne Gron, Durham, NC (US);

Ganesan Sathya, Cary, NC (US);

Assignee:

Affinergy, LLC, Durham, NC (US);

Attorney:

NK Patent Law, PLLC

Primary Examiner:

Karlheinz R Skowronek

Assistant Examiner:

Lianko Garyu

Int. Cl.
CPC ...
A61K 38/10 (2006.01); C07K 17/00 (2006.01); C07K 17/12 (2006.01); C07K 7/08 (2006.01); C07K 17/08 (2006.01); C07K 17/10 (2006.01); A61K 47/48 (2006.01); A61K 47/02 (2006.01); A61K 9/00 (2006.01); A61L 27/54 (2006.01); A61L 27/58 (2006.01); A61K 47/42 (2006.01); A61L 27/42 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48992 (2013.01); A61K 47/48246 (2013.01); A61K 47/02 (2013.01); A61K 9/0024 (2013.01); A61K 38/10 (2013.01); A61L 27/54 (2013.01); A61L 27/58 (2013.01); A61K 47/42 (2013.01); A61L 27/427 (2013.01); A61L 27/425 (2013.01); A61L 2430/02 (2013.01); A61L 2300/414 (2013.01);
Abstract

Compositions and methods for tissue repair are provided including cell binding peptides and growth factor binding peptides. The cell binding peptides bind to one or more of stem cells, fibroblasts, or endothelial cells. The growth factor binding peptides include platelet derived growth factor (PDGF) binding peptides and growth differentiation factor (GDF) binding peptides. The tissue for repair includes tendon, muscle, connective tissue, ligament, cardiac tissue, vascular tissue, or dermis. Implantable devices for tissue repair are provided to which the cell and growth factor binding peptides are attached, such as acellular extracellular matrix having attached binding peptide.

Find Patent Forward Citations

Loading…